Derivatization reagents for gas chromatography and organic synthesis. The protection of polar groups such as carboxylic acids, alcohols and amines with suitable reagents to produce non-polar derivatives, is of great interest in gaschromatography and in organic synthesis. By changing the properties of a sample, it can be made more stable and easier to separate and detect by gaschromatography. A suitable reagent should offer: - ease of reaction
- quantitative reaction
- reproducible yields and results
- no side reactions
- generation of a stable product
- higher volatility of the derivative
- lower detection limit
- enabling of special detection methods (e.g. ECD for fluorine containing derivatives)
Alkylations, acylations and silylations are the most common reactions to derivatize a substrate. Acros Organics is proud to bring you the following reagents commonly used for these derivatizations: | Code | | Acylation | Code | | Alkylation / Esterification | Code | | Silylation | | 16926 | | Heptafluorobutyric anhydride 98+% | 38533 | | (Trimethylsilyl)diazomethane Tech., ca. 2.0M solution in hexanes | 15646 | (BSA) | N,O-bis-(trimethylsilyl)acetamide 95% | | 21007 | (MBTFA) | N-methyl-bis(trifluoroacetamide) 98% | 16125 | | N,N-dimethylformamide dimethyl acetal ca 97% | 16800 | (BSTFA) | N,O-bis(trimethylsilyl)trifluoroacetamide 98+% | | 14712 | | Pentafluorobenzoylchloride 98% | 38136 | NEW | Trimethylsulfonium hydroxide | 16284 | | Chlorodimethylsilane 96% | | 13972 | (TFA) | Trifluoroacetic acid 99% | 42053 | | Tetramethylammoniumhydroxide pentahydrate, 99% | 12058 | | 1,1,1,3,3,3-hexamethyldisilazane 98% | | 29381 | (TFA) | Trifluoroacetic acid, biochemical grade | | | | 38127 | NEW | N-methyl-N-(trimethylsilyl)heptafluorobutyramide | | 14633 | | Pentafluorobenzylbromide | | | | 22158 | (MSTFA) | N-methyl-N-(trimethylsilyl)trifluoroacetamide 97% | | 14781 | | Trifluoroacetic anhydride | | | | 22154 | (MTBSTFA) | N-(tert-butyldimethylsilyl-N-methyltrifluoroacetamide 98% | | 41693 | | Pentafluoropropionic anhydride | | | | 11012 | | Chlorotrimethylsilane 98% | | H/0095 | | Heptafluorobutyryl imidazole | | | | 15569 | (TMSDEA) | N,N-diethyl-1,1,1-trimethylsilylamine 98% | | 37719 | | Trifluoroacetyl imidazole | | | | 16713 | (TSIM) | N-(trimethylsilyl)-imidazole 98% | | 14754 | | Hexafluoroisopropanol | | | | 21595 | (MSA) | N-methyl-N-(trimethylsilyl)acetamide 98% | | 42202 | | Trimethylanilinium hydroxide | | | | | | | | 15890 | | Boron trifluoride dimethanol complex | | | | | | |
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