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Peptide grade solvents and reagents

In response to a growing interest of drug discovery and development chemists in peptides and peptidomimetic compounds, Acros Organics is expanding its portfolio of building blocks, reagents, solvents and solid supports to address the evolving needs of its customers.

A selection of peptide grade reagents, formulations, and solvents has been recently added to our product range and are listed below.  ReadyMix products are peptide grade reagents and solvents in the most popular formulations used by the peptide synthesis chemists.  They are now available from Acros Organics, in ready to use solutions or in kits including pre-weighed amounts of activating agents and solvents to be mixed immediately prior to use.

Acros Organics currently offers a large number of additional compounds that are of interest to the peptide synthesis chemist (a sample of our existing coupling reagents is also included here) with new entries being added every day.  If you cannot find what you need, please inquire via your local Acros Organics distributor.

Peptide grade reagents, solvents and formulations.*

Code Pack. Name Specifications
354800025 2.5L  

Dichloromethane (DCM), peptide synthesis grade

H2O (KF) max 0.005%. Residue on evaporation max 0.0005%.  Free amines (Kaiser) max 0.0001%.
354830025 2.5L N,N-Dimethylformamide (DMF), peptide synthesis grade Acidity max 0.001%. Water (KF) max 0.02%.  Free amines (Kaiser) max 0.001%.  Residue on evaporation max 0.001%. Formaldehyde max 0.002%.
354840025 2.5L Methyl sulfoxide (DMSO), peptide synthesis grade    Water (KF) max 0.005%. Residue on evaporation max 0.001%. Peroxides (as H2O2) max 0.001%. Free amines (Kaiser) not detected.
354861000 100ml 1,1,1,3,3,3-Hexafluoro-2-isopropanol (HFIPA), peptide synthesis grade Water (KF) max 0.02%. Free amines (Kaiser) not detected. Residue on evaporation max 0.0005%.
354890025 2.5L 1-Methyl-2-pyrrolidone, special automatic peptide synthesizer grade

Water (KF) max 0.03%. Residue on evaporation max 0.002%. Free amines (Kaiser) max 0.001%.  UV absorbance: 285nm max 0.065 AU., 300nm max 0.035 AU, 325nm max 0.010 AU., 350nm max 0.005 AU.

354900025 2.5L 1-Methyl-2-pyrrolidone (NMP), peptide synthesis grade       Water (KF) max 0.03%. Residue on evaporation max 0.002%. Free amines (Kaiser) max 0.001%.
354871000 100ml 1,1,1,3,3,3-Hexafluoro-2-isopropanol, 10% in dichloromethane, ReadyMix**, peptide synthesis grade  Water (KF) max 0.01%.
354910010 1L Piperidine, 20% in N-Methyl-2-pyrrolidone, ReadyMix, peptide synthesis grade Prepared from peptide grade materials.
354811000 100ml N,N'-Dicyclohexylcarbodiimide (DCC) 0.1M solution in Dichloromethane, ReadyMix, peptide synthesis grade Prepared from peptide grade materials.
354822000 200ml N,N'-Dicyclohexylcarbodiimide (DCC) in N-Methyl-2-pyrrolidone, ReadyMix, peptide synthesis grade Prepared from peptide grade materials.
354852000 200ml HBTU 0.1M in (HOBT 0.45M in DMF) 1:1, ReadyMix, peptide synthesis grade 3 Bottles kit of pure HBTU, HOBT and DMF to be mixed prior to use to give 3.79% HBTU in [6.08% HOBT in DMF].
354882000 200ml HOBT 0.5M in N,N-dimethylformamide, ReadyMix, peptide synthesis grade 2 Bottles kit of pure HOBT and DMF to be mixed prior to use to give 6.76% HOBT in DMF.

* All peptide grade solvents are available in 1L and 2.5L bottles.

**ReadyMix kits: convenient 200ml size, no tedious preparation, prepared with high quality reagents, complete range of most popular mixes.

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